Genetic analysis for inherited traits: eye color (OCA2, HERC2 genes), hair color (red hair: MC1R; dark/light: KITLG, IRF4, SLC45A2; curly/straight: TCHH), hair thickness (EDAR), freckles (MC1R), bitter taste perception (TAS2R38), sweet taste preference, asparagus metabolite detection (olfactory genes), cilantro preference (OR6A2), sweet vs salty preference, dental traits.
• Free with the purchase of any UNITY package

Next-generation sequencing of all protein-coding regions (exons) representing approximately 1-2% of the genome but containing ~85% of known disease-causing variants. Screens over 5,000 genes associated with inherited diseases. Analyzes single nucleotide variants (SNVs), small insertions/deletions (indels). Results identify pathogenic variants and variants of uncertain significance, providing diagnostic information for suspected genetic disorders.

Sequencing of all fetal exons (protein-coding regions) from cell-free fetal DNA. Detects single nucleotide variants (SNVs) and copy number variations (CNVs) in any clinically relevant gene. Identifies potential genetic causes of structural abnormalities detected on ultrasound or suspected genetic syndromes. Provides comprehensive diagnostic information beyond standard NIPT.

Analysis of cell-free fetal DNA following pregnancy loss. Identifies chromosomal abnormalities that may explain miscarriage including aneuploidies, large copy number variations (CNVs), and structural abnormalities. Provides information for grief support and future pregnancy planning.

Screening for common trisomies (13, 18, 21), sex chromosome aneuploidies (Turner syndrome, Klinefelter syndrome, Triple X, XYY), rare autosomal aneuploidies (RAAs) affecting chromosomes other than 13, 18, 21, large copy number variations (CNVs) greater than 7 megabases, and fetal sex determination.

Cell-free fetal DNA (cfDNA) analysis from maternal blood sample (from 10 weeks gestation). Screens for: Trisomy 13 (Patau syndrome), Trisomy 18 (Edwards syndrome), Trisomy 21 (Down syndrome), Fetal chromosomal sex determination. High sensitivity and specificity for common aneuploidies.

Comprehensive prenatal screening combining two analyses from single maternal blood draw (minimum 10 weeks gestation):
• Carrier screening with single-gene NIPT reflex – tests mother’s DNA for 274+ genetic conditions including cystic fibrosis (CFTR), spinal muscular atrophy (SMN1), fragile X syndrome (FMR1), hemoglobinopathies, and other recessive conditions; if mother tests positive as carrier, automatically analyzes fetal DNA for same condition.
• Aneuploidy screening – Trisomy 13, 18, 21, sex chromosome aneuploidies (XXX, XXY, XYY, monosomy X), 22q11.2 deletion.
• Fetal antigen typing – fetal biological sex, RhD status, and additional red blood cell antigens (C, c, E, e, K) for alloimmunization risk assessment.

Combined testing of Unity Carrier Screen with aneuploidy screening for trisomies 13, 18, 21, and sex chromosome analysis. Comprehensive prenatal genetic assessment in a single blood draw.

Cell-free DNA analysis from maternal blood (minimum 10 weeks gestation). Screens for: Trisomy 13 (Patau syndrome), Trisomy 18 (Edwards syndrome), Trisomy 21 (Down syndrome), 22q11.2 deletion syndrome (DiGeorge syndrome caused by chromosome 22 microdeletion). Includes fetal biological sex determination (XX or XY). Fetal RhD genotyping – determines if Rh-negative mother is carrying Rh-positive or Rh-negative fetus to guide RhIg (RhoGAM) administration decisions. Results provided with risk scores and positive predictive values.

Maternal carrier screening for over 100 genetic conditions including cystic fibrosis, spinal muscular atrophy, hemoglobinopathies, and other recessive disorders. If mother tests positive as carrier, reflex testing of fetal DNA (sgNIPT) for the same condition.

Trisomy 13, 18, and 21 screening, fetal sex determination, fetal RhD status (to assess need for RhoGAM in RhD-negative mothers), 22q11.2 deletion syndrome (DiGeorge syndrome) screening.